Radioligand-binding study of noribogaine, a likely metabolite of ibogaine.
Brain research March 27, 1995 S M Pearl, K Herrick-Davis, M Teitler et al. 78 citations
Noribogaine, a suspected metabolite of ibogaine, binds more strongly than ibogaine to all three types of opioid receptors. Ibogaine had highest affinity for kappa receptors, less for mu, and no measurable affinity for delta receptors. Noribogaine showed higher affinity for kappa, mu, and delta receptors, suggesting it is active in the body and may contribute to ibogaine's effects.