Stimulus effects of ibogaine in rats trained with yohimbine, DOM, or LSD.
Pharmacology, biochemistry, and behavior December 1, 1992 P A Palumbo, J C Winter 26 citations
Ibogaine's effects were tested in rats trained to discriminate yohimbine, DOM, or LSD from no treatment. Ibogaine did not significantly mimic yohimbine, but it partially mimicked DOM and LSD. Pizotyline blocked these effects, suggesting ibogaine's stimulus properties involve 5-HT2 receptor activity, with a possible 5-HT1A contribution.