Lifetime classic psychedelic use and headaches: A cross-sectional study.
Journal of psychopharmacology (Oxford, England) March 12, 2025 Zusanna Bjurenfalk, Alva Cosmo, Otto Simonsson et al. 3 citations
People who had ever used classic psychedelics such as LSD or psilocybin showed 25% lower odds of reporting frequent bad headaches, based on data from over 11,000 British adults. The analysis controlled for many other factors, suggesting a possible protective association. This finding adds to evidence that classic psychedelics might one day be developed as preventive treatments for migraine and cluster headache, though the study cannot prove cause and effect.