Therapeutic Potential of MDMA- and Psychedelic-Assisted Psychotherapy for Adolescent Depression and Trauma.
Current psychiatry reports February 1, 2025 Jamarie Geller, Eric Whitney 3 citations
Clinical trials show psilocybin-assisted psychotherapy for adults with depression and MDMA-assisted psychotherapy for adults with PTSD yield encouraging results, including for treatment-resistant depression and durable remission rates. No studies have examined these treatments in adolescents. Given the high burden of untreated psychiatric illness in youth, investigating safety and efficacy in younger patients is recommended, with research and implementation tailored to adolescent needs and equity considered at every stage.