Mindfulness-integrated Cognitive Behavioral Therapy reduces pain and psychological distress, and improves equanimity, hope and post-traumatic growth during breast cancer treatment: A pilot randomized controlled trial.
European journal of oncology nursing : the official journal of European Oncology Nursing Society June 1, 2025 Mohsen Arefian, Karim Asgari-Mobarake 10 citations
A shortened, four-week version of Mindfulness-integrated Cognitive Behavior Therapy (MiCBT) reduced pain and psychological distress—including depression, anxiety, and stress—and improved equanimity, hope, and post-traumatic growth in women with Stage I-III breast cancer undergoing chemotherapy. In a randomized trial with 42 women, those receiving MiCBT showed large reductions in pain, depression, anxiety, and stress compared with a treatment-as-usual group, along with gains in equanimity, hope, and post-traumatic growth. These benefits persisted at a two-month follow-up. The findings suggest that a brief MiCBT program can improve daily experiences during chemotherapy, though larger studies with active control groups are needed.