EEG microstates during resting-state and dissociative events in patients with psychogenic non-epileptic seizures.
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology May 1, 2025 Cecilia Catania, Marco Mancuso, Adolfo Mazzeo et al. 3 citations
In people with psychogenic non-epileptic seizures (PNES), a type of dissociative event, brain activity patterns shift markedly during the events compared to resting periods. EEG microstate analysis of 22 PNES patients and 24 healthy controls showed that microstate C, linked to the default mode network, was more prominent at rest in patients than in controls, but its duration, coverage, and global field power all decreased significantly during PNES events. This suggests a major change in default mode network dynamics during dissociative events, pointing to a mix of pathological and adaptive brain processes underlying PNES.