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Verena Hinze

2 papers in the library · 4 citations · publishing 2025

Papers

Examining what works for whom and how in mindfulness-based cognitive therapy (MBCT) for recurrent depression: moderated-mediation analysis in the PREVENT trial.

The British journal of psychiatry : the journal of mental science April 1, 2025 Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al. 4 citations

Mindfulness skills mediate the effect of mindfulness-based cognitive therapy (MBCT) on depressive symptoms over 24 months, and this mediation is stronger for people with more severe depression. Among 424 adults with recurrent depression, those with higher severity showed an expected 10-point reduction on the Beck Depression Inventory-II, compared to a 3.5-point reduction for those with lower severity. The findings suggest MBCT with antidepressant tapering support works through a unique mechanism—mindfulness skills—that differs from maintenance medication alone, supporting personalized treatment for recurrent depression.

Adolescents' trajectories of mental health in the MYRIAD trial.

JCPP advances October 7, 2025 Carolina Guzman Holst, Simona Skripkauskaite, Jack L. Andrews et al.

Most adolescents (69%-80%) followed stable low-problem trajectories for depression risk, social-emotional-behavioural functioning, wellbeing, and anxiety over a one-year school-based mindfulness intervention trial. However, 11%-23% experienced stable high-problem trajectories, 2%-16% showed increasing problems, and 1%-5% showed decreasing problems. Receiving the mindfulness intervention did not affect which trajectory adolescents followed. Individual factors like executive functioning difficulties and baseline mental health risk, along with school climate, predicted trajectory membership, but these effects did not differ between intervention and control groups. The findings indicate that universal interventions may not address the diverse needs of all students.