Effectiveness of Mindfulness-Based Cognitive Therapy on Depressive Symptoms, Brain Potential, and Neuroimmunoinflammatory Factors in Depressed Patients.
Clinical neuropharmacology Jiancheng Qiu, Yifei Gong, Xiucui Zhang et al. 4 citations
Adding mindfulness-based cognitive therapy (MBCT) to standard treatment reduces depressive symptoms more than standard treatment alone in people with depression. In a randomized trial with 64 patients, those receiving MBCT plus conventional therapy showed greater decreases on the Hamilton Depression Rating Scale and lower levels of inflammatory markers tumor necrosis factor α and interleukin-6, along with larger increases in quality of life scores, response execution, and serotonin. Brain potential measures also improved, with shorter latency and longer amplitude. The combination therapy appears to suppress inflammation and sharpen attention and response to target stimuli.