The anxiolytic-like effect of the alkaloid fraction of the psychedelic plant Mimosa tenuiflora (Willd.) Poir.
Natural product research September 18, 2024 Jady Vitoria Barjud Pereira Ferreira, Ana Marcia de Freitas Pessoa, Rita de Cassia de Lima Sousa et al. 1 citation
An alkaloid fraction (AF II) from the root bark of Mimosa tenuiflora, containing DMT, reduces anxiety in mice. Female Swiss mice received either saline, AF II (6 mg/kg), or diazepam (5 mg/kg) before being tested in the light-dark box and elevated plus maze. AF II produced significant anxiolytic effects in both tests, comparable to the standard drug diazepam.