Psychedelics as a potential treatment for tobacco use disorder: a systematic review.
Discover mental health September 17, 2024 S K Spoelstra, R A Schoevers, S D Venema et al. 8 citations
Tobacco use disorder remains a major public health problem, and current cessation therapies have limited effectiveness. This review evaluated scientific evidence on psychedelics for smoking cessation by searching four databases up to March 2024. From 1073 articles, 8 publications met inclusion criteria, with 4 originating from a single study. Most studies focused on psilocybin (7 of 8), for which supportive evidence was suggested for treating tobacco use disorder. Research on ayahuasca, mescaline, peyote, LSD, LSA, and DMT was too limited to draw definitive conclusions. There is limited evidence that psychedelics, particularly psilocybin, may offer a potential avenue for combating tobacco use disorder, though more research is needed.