Improved quality of life and psychological symptoms following mindfulness and cognitive rehabilitation in multiple sclerosis and their mediating role for cognition: a randomized controlled trial.
Journal of neurology July 1, 2024 Ilse M Nauta, Maureen Van Dam, Dirk Bertens et al. 20 citations
Mindfulness-based cognitive therapy (MBCT) significantly enhances quality of life for individuals with multiple sclerosis (MS). In a trial involving 99 patients, MBCT improved depressive symptoms (Cohen's d = -0.46) and mental well-being (d = -0.73) at post-treatment, with mindfulness skills showing lasting effects even six months later (d = 0.42). Cognitive rehabilitation therapy (CRT) also reduced depressive symptoms (d = -0.46) but lacked long-term benefits. Both therapies positively impacted self-reported cognitive issues, highlighting their importance in managing MS-related psychological challenges.