Nancy A Haug

2 papers in the library · 95 citations · publishing 2021-2023

Papers

Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial.

Journal of psychopharmacology (Oxford, England) February 1, 2021 Rebecca L Rothberg, Nour Azhari, Nancy A Haug et al. 95 citations

In alcohol-dependent adults seeking treatment, a single sub-anesthetic dose of ketamine combined with motivational enhancement therapy produced greater mystical-type experiences and reduced at-risk drinking compared to an active control (midazolam). The mystical-type effects, measured by the Hood Mysticism Scale, mediated ketamine's effect on drinking behavior, whereas dissociation did not. Forty participants were randomized and followed for three weeks post-infusion. The findings suggest that the mystical-type psychoactive effects of ketamine may be important for its therapeutic benefit in addiction treatment.

DOI: 10.1177/0269881120970879 Full text Ketamine Alcohol use disorder Mystical experience Addiction treatment +5

Development and initial validation of an MDMA/Ecstasy motives assessment.

Addictive behaviors January 1, 2023 James E Sottile, Kathryn S Macia, Robert E Wickham et al.

MDMA/Ecstasy users are motivated by social, expansion, coping, and energy factors, distinct from the motives for alcohol, cannabis, or methamphetamine use. A new four-factor motives scale was developed from an international online sample of 1,754 adults. The scale showed good internal consistency and validity, with social, expansion, coping, and energy motives emerging as significant, while conformity and enhancement did not. The findings highlight the unique stimulating, emotional, and empathic effects sought by recreational MDMA/Ecstasy users, which can inform treatment interventions and harm reduction policies.

DOI: 10.1016/j.addbeh.2022.107494 Full text Ecstasy MDMA Molly Harm reduction +1