Daniel Sippel

Department of Psychiatry and Psychotherapy, University Hospital of Tuebingen, Tübingen Center for Mental Health (TüCMH), Tuebingen, Germany; German Center for Mental Health (DZPG), partner site Tuebingen, Germany.

2 papers in the library · 9 citations · publishing 2023-2025

Papers

In situ fNIRS measurements during cognitive behavioral emotion regulation training in rumination-focused therapy: A randomized-controlled trial.

NeuroImage. Clinical January 1, 2023 Hendrik Laicher, Isabell Int-Veen, Leonie Woloszyn et al. 9 citations

Mindfulness-based Emotion Regulation Training (MBERT) reduces depressive symptoms and rumination in people with major depressive disorder. During emotion regulation exercises, brain activity increased in the bilateral inferior frontal gyrus and dorsolateral prefrontal cortex, key regions of the cognitive control network. Across training sessions, oxygenation in the dorsolateral prefrontal cortex decreased, suggesting neural adaptation. The study used functional near-infrared spectroscopy to measure brain activity during therapy sessions in 42 participants.

DOI: 10.1016/j.nicl.2023.103525 Full text Emotion regulation In situ measurements Major depression Psychotherapy

Psychedelics for the Treatment of Substance Use Disorders

SUCHT - Zeitschrift für Wissenschaft und Praxis / Journal of Addiction Research and Practice December 1, 2025 Johannes Klaus, Fritz Schneider, Rena Schaletzky et al.

An umbrella review of 13 systematic reviews and meta-analyses examined the efficacy of classic and non-classic psychedelics (LSD, psilocybin, ayahuasca, mescaline, and ibogaine) for treating substance use disorders, including alcohol, tobacco, opioid, and cannabis use disorders. Only two reviews performed meta-analyses; the rest provided narrative syntheses. Twelve reviews were rated critically low in methodological quality, and one was rated low. While some reviews reported promising effects, particularly for alcohol use disorder, others concluded the evidence remains inconclusive or inconsistent. Overlap of primary studies across reviews was slight. The overall evidence base is limited by methodological weaknesses and inconclusive results.

DOI: 10.1024/0939-5911/a000953 Alcohol use disorder MDMA Systematic review Substance use +7