NeuroImage. Clinical
January 1, 2021
Eva Blondiaux, Lukas Heydrich, Olaf Blanke
33 citations
Autoscopic phenomena—the illusion of seeing a second own body in external space—take three forms: autoscopic hallucination, heautoscopy, and out-of-body experience. Using lesion network mapping in 26 neurological patients, all three forms localized to a common brain network centered on the bilateral temporo-parietal junction. Each type also showed distinct functional connectivity patterns: out-of-body experiences connected to the angular gyrus, precuneus, and inferior frontal gyrus; autoscopic hallucinations to the precuneus, inferior temporal gyrus, and cerebellum; heautoscopy to the left inferior frontal gyrus, insula, and parahippocampus. The temporo-parietal junction is the core region for all autoscopic phenomena, with each form recruiting additional sensorimotor and self-related subnetworks.
NeuroImage. Clinical
January 1, 2023
Hendrik Laicher, Isabell Int-Veen, Leonie Woloszyn et al.
9 citations
Mindfulness-based Emotion Regulation Training (MBERT) reduces depressive symptoms and rumination in people with major depressive disorder. During emotion regulation exercises, brain activity increased in the bilateral inferior frontal gyrus and dorsolateral prefrontal cortex, key regions of the cognitive control network. Across training sessions, oxygenation in the dorsolateral prefrontal cortex decreased, suggesting neural adaptation. The study used functional near-infrared spectroscopy to measure brain activity during therapy sessions in 42 participants.
NeuroImage. Clinical
January 1, 2025
Zhenyu Liu, Shanshan Wu, Shuwei Wang et al.
7 citations
Patients with disorders of consciousness who received high-frequency repetitive transcranial magnetic stimulation over the dorsolateral prefrontal cortex, in addition to conventional therapy, were three times more likely to show improvement in consciousness level compared to those receiving only conventional therapy. The trial included 48 patients in a randomized controlled design. The stimulated group also showed better scores on a clinical global improvement scale and a reduction in a specific brain microstate (microstate E), suggesting the treatment may help restore balance among cerebral functional networks.
NeuroImage. Clinical
January 1, 2024
Antje Opitz, Josua Zimmermann, David M Cole et al.
2 citations
Chronic users of methamphetamine and MDMA show similar deficits in conflict control and emotional processing, rather than substance-specific differences. In an emotional face-word Stroop task with anger and happy faces, both user groups exhibited smaller behavioral effects of cognitive-emotional conflict and selective impairments in processing anger, compared to amphetamine-naïve controls. These deficits were accompanied by stronger P3 event-related potential modulations, indicating altered stimulus-response mapping and decision-making. The findings suggest that chronic use of substituted amphetamines may affect noradrenergic systems, which could underlie the observed similarities. Understanding noradrenaline's role in these processes is an important direction for future research.