Psilocybin decreases neural responsiveness and increases functional connectivity while preserving pure-tone frequency selectivity in mouse auditory cortex
Journal of Neurophysiology May 29, 2024 Adam T Brockett, Nikolas A Francis 8 citations
Psilocybin alters how the auditory cortex balances internally generated neural activity against incoming sound-driven signals, based on two-photon imaging of awake mice. This modulation may help explain why musical experience during psilocybin-assisted therapy predicts treatment outcomes for neuropsychiatric conditions.