Mechanisms of psilocybin on the treatment of posttraumatic stress disorder
Journal of Psychopharmacology October 3, 2024 Charles Q. Choi, Danica E. Johnson, David Chen‐li et al. 11 citations
Posttraumatic stress disorder (PTSD) can develop after a traumatic event, causing intrusive re-experiencing, mood and cognitive changes, and altered arousal. Few treatments help patients who cannot access or do not benefit from conventional psychotherapy or pharmacotherapy. This review examines the neurobiology of PTSD and psilocybin's mechanism of action, suggesting that psilocybin may be an underexplored treatment option based on pharmacodynamic and psychoanalytic principles, though further research is needed.