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João Ariel Bonar Fernandes

Universidade Federal de São Paulo

2 papers in the library · 55 citations · publishing 2022-2026

Papers

Classic and non‐classic psychedelics for substance use disorder: A review of their historic, past and current research

Addiction Neuroscience June 22, 2022 Fúlvio Rieli Mendes, Cristiane Dos Santos Costa, Victor Distefano Wiltenburg et al. 55 citations

Substance use disorder (SUD) affects millions globally, often impairing brain reward circuits and personal life. Treatments face challenges like limited availability and poor patient retention. A non-systematic review of studies published through December 2021 examined classic (LSD, DMT, psilocybin, mescaline) and non-classic (ibogaine, ketamine, MDMA, salvinorin A, THC) psychedelics for SUD. Results are inconclusive for LSD, DMT, mescaline, MDMA, and salvinorin A. Moderate evidence supports psilocybin and ketamine for alcohol use disorder, ketamine for opiate and alcohol withdrawal, and THC preparations for reducing withdrawal in cannabis and possibly opioid use disorder. Psychedelics appear more effective as adjunct therapy. More research is needed.

The purpose of the psychosocial protocol in the psychedelic-assisted therapy: A scoping review

Journal of Psychopharmacology June 26, 2026 Flavia Giaffone de Paiva Ferreira, João Ariel Bonar Fernandes, Renato Filev et al.

A scoping review categorized psychosocial protocols used in psychedelic research for mental health treatment. Seven categories were defined, reflecting distinct emphases on the substance, participant, research team, and sociocultural context. Although limited reporting and heterogeneity remain methodological challenges, the proposed parameters suggest a shared language to describe, compare, and examine psychosocial protocols across studies, reducing conceptual uncertainty. The review may facilitate research decision-making and support structured, replicable study designs while allowing flexibility for individualized and culturally responsive care. Explicitly defining the intended purpose of psychosocial protocols could improve transparent reporting and evaluation.