Psychedelics, epilepsy, and seizures: a review
Frontiers in Pharmacology January 12, 2024 Ninon Freidel, Liliane Kreuder, Brenden Samuel Rabinovitch et al. 11 citations
Clinical trials of psychedelics for neurological and psychiatric disorders have systematically excluded people with past or current seizures, despite a lack of evidence that supervised psychedelic use causes or worsens seizures. No clinical trial or preclinical seizure model has shown that psychedelics induce seizures. This review presents cases where individuals experienced either seizures or seizure remission after psychedelic use, with the overall trend indicating safety in controlled clinical settings. The authors propose future research directions to include this population.