Recommendations and Consensus Statements on Psilocybin-Assisted Psychotherapy (PAP) for Depression: A Rapid Review and Thematic Analysis
Open Science Framework January 1, 2025 Aimée Freeburn, Alene Sze Jing Yong, Simon Bell
Clinical guidelines and position statements from multiple countries recommend medical psilocybin-assisted psychotherapy for adults with depression, but they vary in their specific conditions and safeguards. The review of international documents shows consensus that PAP should be administered in controlled clinical settings with trained therapists, though recommendations differ on patient selection criteria, dosing protocols, and integration procedures. Most guidelines emphasize the need for further research to establish long-term safety and efficacy.