Effects of External Stimulation on Psychedelic State Neurodynamics.
ACS chemical neuroscience February 7, 2024 Pedro A M Mediano, Fernando E Rosas, Christopher Timmermann et al. 60 citations
LSD increases brain entropy (neural signal diversity) across all conditions, but the effect is strongest when eyes are closed. Brain entropy changes correlate with subjective psychedelic experience ratings, except when viewing a video, possibly because external stimuli compete with LSD-induced imagery. This shows context modulates neural dynamics during psychedelic experiences, highlighting the importance of environment in psychedelic psychotherapy.