Ginastera au bout de l'archet
Scientific Reports February 18, 2009 Vincent Haegele 38 citations
Both MDMA and psilocybin reduce the rejection of unfair offers in the Ultimatum Game, a measure of costly punishment of norm violators. In two studies with healthy participants, psilocybin (open-label, within-participant, N=19) and MDMA (placebo-controlled, double-blind, crossover, N=20) lowered rejection rates (odds ratios 0.42 and 0.57, respectively). For MDMA, the reduction correlated with increased prosociality (R²=0.26). MDMA did not affect third-party rejection but increased amounts offered to others (Cohen's d=0.82). The findings suggest these compounds shift the concept of social reward toward direct relationship value, informing their use in drug-assisted psychotherapy.