Predicting Cardiovascular Collapse in Critically Ill Patients During Intubation Induction: A Prospective Observational Study.
Medicina (Kaunas, Lithuania) January 15, 2026 Ömer Emgin, Gamze Taşkan, Aytuğ Yıldız et al.
Among 130 intensive care unit patients, 47.7% experienced peri-intubation cardiovascular collapse (PIC). Age Shock Index (Age-SI) had the highest predictive accuracy for PIC. Ketamine was associated with a reduced risk of PIC (odds ratio 0.161), while propofol (odds ratio 2.962), older age, higher lactate, and higher Diastolic Shock Index were independent risk factors. ICU mortality was markedly higher in patients who developed PIC (74.2% vs. 20.6%). These findings support using Age-SI and other shock indices for risk assessment and selecting ketamine over propofol to lower PIC risk during ICU intubation.