Frederick Streeter Barrett

Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Behavioral Pharmacology Research Unit, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

3 papers in the library · 21 citations · publishing 2017-2023

Papers

The psychedelic effects of cannabis: A review of the literature

Journal of Psychopharmacology November 10, 2023 David Wolinsky, Frederick Streeter Barrett, Ryan Vandrey 16 citations

Cannabis, especially high-THC varieties, may be able to produce perceptual changes, aversiveness, and mystical experiences similar to those caused by classic psychedelics like psilocybin. Although cannabis is not typically regarded as having psychedelic effects in modern research, historical use alongside psychedelics suggests otherwise. The review finds that recent controlled studies may have failed to observe these effects due to the doses, set, and settings used. Further research is needed to test high doses of THC in therapeutic contexts similar to those used for psychedelics. If cannabis can reliably generate psychedelic experiences, it could be explored as an adjunctive treatment for psychiatric disorders and as an active comparator in clinical trials.

DOI: 10.1177/02698811231209194 Mystical experience Psilocybin Altered consciousness THC +6

Psilocybin in long-term meditators: Effects on default mode network functional connectivity and retrospective ratings of qualitative experience

Drug and Alcohol Dependence January 21, 2017 Frederick Streeter Barrett, Matthew W. Johnson, Roland R. Griffiths 5 citations

No Summary

DOI: 10.1016/j.drugalcdep.2016.08.058 Smoking cessation Nicotine patch Nicotine gum Abstinence +8

Psychedelic resting-state neuroimaging: A review and perspective on balancing replication and novel analyses.

Neuroscience and biobehavioral reviews July 1, 2022 Drummond E-Wen Mcculloch, Gitte Moos Knudsen, Frederick Streeter Barrett et al.

A large group of psychedelic imaging researchers reviewed 42 articles from 17 unique studies that used resting-state functional magnetic resonance imaging (rs-fMRI) to examine psychedelic effects. They found that nearly all studies varied in data processing and analysis methods, two datasets underpin over half of the published literature, and key outcome terms are used ambiguously. The authors recommend guidelines to improve consistency and replicability in future research, arguing that the field must balance novel methods with standardized approaches to reliably understand the neural mechanisms of psychedelics.

DOI: 10.1016/j.neubiorev.2022.104689 Full text DMT LSD Psilocin Psilocybin +10