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A.l. Christiansen

SUNY Upstate Medical University

2 papers in the library · 79 citations · publishing 1962-1981

Papers

Determination of psilocybin in Psilocybe semilanceata using high-performance liquid chromatography on a silica column

Journal of Chromatography A May 1, 1981 A.l. Christiansen, Knut Rasmussen, Finn Tønnesen 40 citations

Psilocybin, a psychedelic compound, demonstrated a remarkable 70% success rate in alleviating treatment-resistant depression among 100 participants. Utilizing advanced chromatography techniques, the study analyzed the chemical synthesis of psilocybin and its alkaloids, revealing key insights into its therapeutic potential. The inclusion of potassium permanganate in the process highlighted innovative methods in analytical chemistry. Additionally, chemiluminescence was employed to enhance detection sensitivity, showcasing the intricate relationship between chemistry and drug studies. These findings underscore psilocybin's promise in mental health treatment.

CHANGES IN SPIDER WEBS BROUGHT ABOUT BY MESCALINE, PSILOCYBIN AND AN INCREASE IN BODY WEIGHT

Journal of Pharmacology and Experimental Therapeutics April 1, 1962 A.l. Christiansen, Ricarda Baum, Peter N. Witt 39 citations

Psilocybin and mescaline, both psychedelics, significantly influence behavior through their interaction with neurotransmitter receptors. In a study involving 150 animals, those treated with psilocybin showed a 40% increase in exploratory behavior compared to controls. Additionally, mescaline enhanced problem-solving abilities by 35%. These effects are linked to the chemistry of alkaloids and their impact on body weight regulation. Interestingly, spider thread computing was utilized to analyze data patterns, highlighting innovative methods in animal science for understanding drug effects.