Maudsley Hospital
2 papers in the library · 41 citations · publishing 1958
Journal of Mental Science October 1, 1958 J. C. Brengelmann, C. M. B. Pare, M. Sandler 31 citations
Injecting 5-hydroxytryptophan before lysergic acid diethylamide reduces the psychological effects of LSD, supporting the hypothesis that serotonin acts to diminish those effects. Placebo-controlled psychological tests showed this reduction.
Journal of Mental Science October 1, 1958 J. C. Brengelmann 10 citations
This analysis examines an experiment by Brengelmann, Pare, and Sandler that investigated whether 5-hydroxytryptophan (5-HTP) alters the effects of lysergic acid diethylamide (LSD) as measured by psychological tests. The discussion focuses on problems with measuring and validating the concept of LSD-induced psychosis, questioning whether psychological tests can reliably capture the drug's effects.