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K. N. Houk

1 paper in the library · 72 citations · publishing 1977

Papers

Photoelectron spectra of psychotropic drugs. 1. Phenethylamines, tryptamines, and LSD

Journal of the American Chemical Society June 1, 1977 L. N. Domelsmith, Linda L. Munchausen, K. N. Houk 72 citations

The photoelectron spectra of 27 phenethylamines, tryptamines, and LSD were measured and interpreted using semi-empirical molecular orbital calculations. The ionization potentials of these psychotropic drugs correlate with their known pharmacological activities. The spectra provide information about the electronic structures of these molecules, which can be related to their interactions with biological receptors.