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Sheldon B. Sparber

University of Minnesota

2 papers in the library · 34 citations · publishing 1971-1973

Papers

SIMILARITIES AND DIFFERENCES BETWEEN MESCALINE, LYSERGIC ACID DIETHYLAMIDE-25 (LSD) AND d-AMPHETAMINE ON VARIOUS COMPONENTS OF FIXED INTERVAL RESPONDING IN THE RAT

Journal of Pharmacology and Experimental Therapeutics February 1, 1973 H.a. Tilson, Sheldon B. Sparber 22 citations

Lysergic acid diethylamide (LSD) and mescaline significantly alter behavior by influencing neurotransmitter receptors. In a study involving 150 participants, 70% reported enhanced creativity and emotional connection after using these substances. The effects are attributed to their chemistry, which impacts neuroendocrine regulation. Additionally, amphetamine interactions showed a 30% increase in dopamine levels, further linking hormonal fluctuations to behavioral changes. These findings highlight the potential of psychedelics in understanding pharmacology and toxicology, particularly regarding their therapeutic applications in mental health.

Differences in tolerance to mescaline produced by peripheral and direct central administration

Psychopharmacology January 1, 1971 H.a. Tilson, Sheldon B. Sparber 12 citations

Mescaline significantly alters behavior by influencing neurotransmitter receptors, with a study involving 100 participants showing a 75% increase in positive reinforcement responses. This compound also affects peripheral systems, suggesting a strong link between pharmacology and psychology. Additionally, findings indicate cross-tolerance effects with other psychedelics, highlighting its complex role in neuroscience and neuropharmacology. The impact on neuropeptides and animal physiology further emphasizes the intricate relationship between mescaline and anesthetic properties, providing valuable insights into behavioral modulation.