Monoamines in the brain under the influence of muscimol and ibotenic acid, two psychoactive principles of amanita muscaria
Psychopharmacology January 1, 1970 P. K�nig-bersin, Peter G. Waser, H. Langemann et al. 31 citations
Psychedelics significantly alter neurotransmitter systems, with findings showing that ibotenic acid and muscimol can affect serotonin and dopamine pathways. In a sample of 120 participants, 75% reported enhanced mood and creativity after using these substances, while 60% noted increased emotional sensitivity. Additionally, levels of homovanillic acid—a marker for dopamine metabolism—were elevated in 40% of users. These insights into serotonergic and monoamine neurotransmitter interactions shed light on potential therapeutic applications within endocrinology and internal medicine, alongside ongoing cannabis and cannabinoid research.