LYSERGIC ACID DIETHYLAMIDE TARTRATE (LSD-25) DOSAGE LEVELS, GROUP DIFFERENCES, AND SOCIAL INTERACTION
The Journal of Nervous and Mental Disease August 1, 1971 Frances E. Cheek, Carolyn M. Holstein 15 citations
Lysergic acid diethylamide (LSD-25) alters social interaction in ways that depend on both dosage and group composition. In four groups—reformatory inmates, two groups of alcoholics, and chronic schizophrenics—total interaction increased at lower doses (25 and 50 μg), leveled off at 75 and 100 μg, and decreased at 200 μg. However, the type of change varied: reformatory inmates showed more negative social-emotional behaviors, alcoholics showed more positive behaviors, and schizophrenics increased in both positive and negative behaviors. Self-analytic behavior rose markedly at higher doses only in one alcoholic group. These findings help explain contradictions in earlier studies and have implications for therapeutic and illicit LSD use.