Participants in ayahuasca rituals at a substance-use-disorder treatment center in Uruguay scored higher than a control group on Impulsive Sensation Seeking, Boredom Susceptibility, and Social Warmth scales of the Zuckerman-Kuhlman-Aluja Personality Questionnaire. Qualitative analysis of their experiences revealed five categories: emotional experiences (including love and empathy), corporal experiences, spiritual/transcendental experiences, personal experiences, and visions. The findings suggest that the combination of social interactions and ayahuasca's pharmacological action may facilitate social emotions during rituals and contribute to long-term increases in empathic and social aspects of personality.
Ayahuasca's psychological and subjective effects differ between two neoshamanic groups in Uruguay: a psychospiritual holistic center and a center treating substance use disorders. A mixed-methods study using the Hallucinogen Rating Scale and in-depth interviews found significant medium-sized differences in affect, cognition, and perception between groups. The group with higher scores reported more frequent and complex emotional, cognitive, and perceptive experiences. No significant quantitative differences emerged for intensity or somaesthetic domains, yet qualitative reports described the experience as “soft” in one group and noted bodily effects like purging. Stronger subjective effects may relate to differences in dosage and setting.