A review of the acute subjective effects of MDMA/ecstasy
Addiction March 24, 2006 Chelsea A. Baylen, Harold Rosenberg 214 citations
A review of 24 studies on the acute subjective effects of MDMA/ecstasy identified a set of effects consistently reported across multiple investigations. The most common effects were emotional (anxiety, depression, closeness, fear, euphoria, calmness) and somatic (nausea/vomiting, bruxism, muscle aches/headache, sweating, numbness, body temperature changes, fatigue, dizziness, dry mouth, increased energy). Only one sexual effect (sexual arousal), one cognitive effect (confused thought), one sensory-perceptual effect (visual changes), one sleep-related effect (sleeplessness), and one appetite-related effect (decreased appetite) were reported in five or more studies. Three factors—time since ingestion, dose level, and gender—influence the acute subjective experience.