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Dietrich Lehmann

3 papers in the library · 664 citations · publishing 2001-2013

Papers

Psychobiology of Altered States of Consciousness.

Psychological Bulletin January 1, 2005 Dieter Vaitl, Niels Birbaumer, John Gruzelier et al. 446 citations

Altered states of consciousness (ASC) can occur spontaneously, be evoked by physical or physiological stimulation, induced by psychological means, or caused by diseases. Psychological and neurobiological approaches reveal four dimensions characterizing ASC: activation, awareness span, self-awareness, and sensory dynamics. Neurophysiologically, different states of consciousness arise from compromised brain structure, transient changes in brain dynamics (disconnectivity), and neurochemical and metabolic processes. Environmental stimuli, mental practices, and self-control techniques can also temporarily alter brain functioning and conscious experience.

Localization of MDMA‐induced brain activity in healthy volunteers using low resolution brain electromagnetic tomography (LORETA)

Human Brain Mapping August 27, 2001 Edi Frei, Alex Gamma, Roberto D. Pascual‐marqui et al. 175 citations

A single dose of MDMA (1.7 mg/kg) in 16 healthy, MDMA-naïve volunteers produced widespread decreases in slow and medium frequency brain activity and increases in fast frequency activity in the anterior temporal and posterior orbital cortex, as measured by scalp EEG and low resolution brain electromagnetic tomography (LORETA). These changes were accompanied by heightened mood, emotional arousal, and increased extraversion. The EEG pattern suggests that serotonin, noradrenaline, and, to a lesser degree, dopamine contribute to MDMA's effects on brain activity and possibly mood and behavior, indicating modulation of limbic orbitofrontal and anterotemporal structures involved in emotional processes.