University of Toronto
2 papers in the library · 144 citations · publishing 2001-2003
Neurology April 10, 2001 Konstantine K. Zakzanis, Donald A. Young 122 citations
Over one year, fifteen people who continued using MDMA showed a progressive decline in immediate and delayed recall on memory tests, even after being abstinent for two weeks at both the initial and follow-up assessments. The findings suggest that ongoing MDMA use is linked to worsening memory function.
Cognitive Neuropsychiatry January 1, 2003 Konstantine K. Zakzanis, Donald A. Young, Zachariah Campbell 22 citations
Repeated recreational use of MDMA (Ecstasy) is linked to lasting impairments in explicit memory. In this study, 15 abstinent MDMA users and 17 matched controls completed tests of memory and vocabulary. MDMA users showed deficits in episodic prospective memory—remembering to perform future tasks—with medium to large differences on time-based and event-based subtests. The ability to recall a future appointment appeared related to how often and how many times MDMA had been used. Further research is needed to explore the neurological basis of these deficits, particularly the role of serotonin.