Neuroimaging in moderate MDMA use: A systematic review
Neuroscience & Biobehavioral Reviews December 30, 2015 Felix Mueller, Claudia Lenz, Markus Steiner et al. 68 citations
Moderate use of MDMA (ecstasy) shows no convincing evidence of structural or functional brain alterations in neuroimaging studies. A review of 19 studies, each involving subjects with fewer than 50 lifetime episodes or under 100 tablets consumed, found no significant harmful effects. However, the lack of results is linked to high methodological variability in dosages and co-consumption of other drugs, low study quality, and small sample sizes.