Methylenedioxyamphetamine (MDA) produces a subjective experience distinct from both LSD and amphetamine, characterized by enhanced emotional communication, empathy, and a sense of closeness to others, without the perceptual distortions typical of LSD or the drive of amphetamine. The effects are described as warm, loving, and facilitative of interpersonal contact, with users reporting a clear sensorium and minimal anxiety. The article notes that MDA's effects are dose-dependent and that it can be used therapeutically to enhance psychotherapy by promoting emotional openness.
In a controlled trial, dipropyltryptamine (DPT)-assisted psychotherapy was compared to conventional group therapy for alcoholics. The DPT group received a single high-dose session plus preparatory and follow-up psychotherapy, while the control group received standard group therapy. At 6-month follow-up, the DPT group showed significantly greater improvement on measures of alcohol abstinence and psychosocial adjustment. The authors suggest that a single DPT session combined with psychotherapy may enhance treatment outcomes for alcoholism, though the small sample size limits generalizability.