Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3,4-methylenedioxymethamphetamine (MDMA)
Synapse February 1, 2000 Bryan Horan, Eliot L. Gardner, Charles R. Ashby 50 citations
Rats given the recreational drug MDMA (ecstasy) for four days later showed a stronger conditioned place preference for cocaine than rats given a placebo, indicating that prior MDMA exposure may increase sensitivity to cocaine's rewarding effects and potentially raise the risk of cocaine addiction.