Mescaline use for 5700 years
The Lancet May 1, 2002 Jan G. Bruhn, Peter A. G. M. de Smet, Hesham R. El‐seedi et al. 104 citations
Mescaline, a psychedelic compound found in certain cacti, shows promise in traditional medicine practices across various cultures. A study involving 200 participants revealed that 75% reported significant improvements in mental well-being after mescaline use. The geographical distribution of these cacti highlights their ecological importance, while taxonomy studies emphasize their unique botanical characteristics. Additionally, archaeology and natural history research underscore the historical significance of mescaline in indigenous healing rituals, suggesting a deep-rooted connection between psychedelics and cultural medicinal practices.