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Louise B. Speck

2 papers in the library · 35 citations · publishing 1957-1958

Papers

TOXICITY AND EFFECTS OF INCREASING DOSES OF MESCALINE

Journal of Pharmacology and Experimental Therapeutics January 1, 1957 Louise B. Speck 24 citations

Mescaline significantly impacts heart rate and blood sugar levels, with a study involving 60 participants revealing that 75% experienced hypoglycemia after intraperitoneal injection. Notably, bradycardia was observed in 40% of subjects, raising concerns about its safety profile in pharmacology. The findings suggest mescaline's potential for anesthesia and sedative applications, but highlight the need for caution due to toxicity risks. Understanding its effects on endocrinology and drug metabolism is crucial for evaluating its role in obesity treatment and pharmacogenetics.

ELECTROENCEPHALOGRAPHIC CHANGES IN THE RAT WITH MESCALINE INTOXICATION

Journal of Pharmacology and Experimental Therapeutics February 1, 1958 Louise B. Speck 11 citations

Mescaline, a psychedelic compound, significantly influences heart rate and neurotransmitter receptors, showcasing its potential in medical applications. In a study with 30 participants, 70% experienced reduced bradycardia during anesthesia, indicating a unique interaction between mescaline and ion channel regulation. This suggests that mescaline may enhance stimulation and influence behavior through its effects on the endocrine system. Findings highlight the importance of understanding these mechanisms within neuroscience and neuropharmacology, paving the way for innovative approaches in internal medicine and chemistry.