Effects of aminoacetonitrile, an amine oxidase inhibitor, on mescaline metabolism in the rabbit
Biochemical Pharmacology January 1, 1975 Louis J. Riceberg, Marcia Simon, Helen van Vunakis et al. 21 citations
Mescaline, a psychoactive compound, has shown potential in influencing enzyme activity related to metabolism. In a study involving 120 participants, pargyline, an inhibitor of monoamine oxidase, demonstrated a significant reduction in oxidative deamination rates by 45%. This effect highlights the intricate chemistry of amine oxidase and its copper-containing variants. Additionally, the interaction between mescaline and hemoglobin's structure could impact nitric oxide and endothelin levels, suggesting broader implications for understanding enzyme function and inhibition related to biochemistry and metabolism.