Neuromyal blocking action of mescaline
American Journal of Physiology-Legacy Content June 1, 1961 Robert T. Schopp, William F. Kreutter, Steven V. Guzak 13 citations
Injecting mescaline directly into an artery partially or completely paralyzes skeletal muscle in dogs. Mescaline and curare together enhance each other's muscle-depressing effects. After mescaline causes full blockade, the muscle still responds to direct electrical stimulation. In chronically denervated muscle, mescaline does not immediately reduce contractions. Adrenaline, potassium chloride, and prostigmine can counteract mescaline-induced paralysis. The paralyzing action of mescaline occurs at the neuromuscular junction.