De novo sequencing and analysis of Lophophora williamsii transcriptome, and searching for putative genes involved in mescaline biosynthesis
BMC Genomics September 1, 2015 Enrique Ibarra‐laclette, Flor Zamudio Hernández, Claudia Pérez-torres et al. 26 citations
High-throughput transcriptome sequencing (RNA-seq) identified candidate genes—tyrosine/DOPA decarboxylase, hydroxylases, and O-methyltransferases—likely involved in mescaline biosynthesis in Lophophora williamsii. This provides a theoretical basis for designing bioassays to confirm these genes' roles in mescaline production.