Mescaline elicits behavioral effects in cats by an action at both serotonin and dopamine receptors
European Journal of Pharmacology December 1, 1983 Michael E. Trulson, Terriann Crisp, Leslie J. Henderson 21 citations
Pretreating cats with low doses of either a serotonin antagonist (methysergide) or a dopamine antagonist (haloperidol) nearly completely blocked the characteristic behavioral effects of mescaline. These blocking effects were specific: methysergide did not block apomorphine's effects, and haloperidol did not block 5-methoxy-N,N-dimethyltryptamine's effects. The findings indicate that mescaline's behavioral effects depend on simultaneous action at both serotonin and dopamine receptors.