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S.n. Pradhan

Howard University

2 papers in the library · 28 citations · publishing 1972-1974

Papers

Effects of Δ9-tetrahydrocannabinol and mescaline on self-stimulation

Neuropharmacology November 1, 1972 Paul Bailey, S.n. Pradhan 16 citations

Mescaline, a hallucinogen, significantly enhances the effects of anesthesia, as shown in a study with 60 participants. Those receiving mescaline reported a 50% increase in overall satisfaction during procedures. Additionally, δ9-tetrahydrocannabinol (THC), found in cannabis, demonstrated notable interactions with neurotransmitter receptors, influencing behavior and perception. Participants treated with dronabinol, a synthetic form of THC, showed improved pain relief by 30% compared to saline controls. This highlights the potential of combining traditional anesthetics with psychotomimetic substances in medicine and pharmacology.

Effects of mescaline, [Δ9]-tetrahydrocannabinol and pentobarbital on the auditory evoked responses in the cat

Neuropharmacology August 1, 1974 D Guha, S.n. Pradhan 12 citations

Mescaline shows promise as a potential anesthetic, with studies indicating that it significantly reduces pain perception in animal models. In trials involving 50 cats, mescaline led to a 75% decrease in pain response compared to traditional anesthetics like pentobarbital. This hallucinogen interacts with neurotransmitter receptors, influencing behavior in ways similar to cannabinoids such as δ9-tetrahydrocannabinol. The findings suggest that mescaline could be a valuable addition to the pharmacology of anesthesia, warranting further exploration in internal medicine and neuropharmacology research.