A Clinical and Metabolic Study of Acute Intoxication with Cannabis Sativa and its Role in the Model Psychoses
Journal of Mental Science October 1, 1958 Frances R. Ames 184 citations
Giving oral doses of hashish, also known as marihuana or dagga, produces mental disturbances similar to those caused by mescaline and lysergic acid. Because these changes resemble symptoms of schizophrenia, some researchers have proposed using such drug-induced “model psychoses” to study the mechanisms and causes of natural psychoses. Cannabis has received less attention than mescaline and lysergic acid, likely because its chemistry is not fully understood and plant preparations are difficult to standardize and vary in potency.