Acute Kidney Failure and Myocarditis Triggered by Magic Mushroom Toxicity in a Patient With Prior Cocaine Exposure
Cureus November 12, 2025 Aung Phyo Oo, Sarah Tseu, Arvind Ponnusamy
A middle-aged man with past cocaine use developed severe anuric acute kidney injury requiring dialysis after magic mushroom poisoning. He also experienced supraventricular tachycardia, elevated troponin T, and severe left ventricular dysfunction, attributed to possible myocarditis from the mushrooms. Imaging showed extensive thrombosis in the abdominal aorta, superior mesenteric artery, and bilateral iliac arteries, causing right kidney infarction and a pulmonary embolism. While psilocybin may theoretically induce vasoconstriction, direct evidence linking it to thrombosis remains limited.