The therapeutic potential of psilocybin in depression resistant to psychotropic drugs
European Psychiatry March 1, 2023 J. Ramírez González, I. Fernández Márquez, Serafín González et al.
Psilocybin microdoses (10–25 mg) combined with psychotherapy improve depressive symptoms in patients with drug-resistant depressive disorder, with benefits lasting at least six months. A review of 19 recent studies found that one or two such doses produce statistically significant improvement. These findings offer optimism for new mental health treatments.