Model Psychoses Induced by LSD-25 in Normals
A M A Archives of Neurology & Psychiatry June 1, 1956 Nicholas A. Bercel 35 citations
Experimental psychosis research has a long history, possibly beginning with Cannabis indica administered to ancient Hun warriors. Scientific experimental psychiatry emerged in the late 19th century during the Kraepelinian era, when the organic theory of psychoses was prominent. Beringer's experiments with mescaline marked a milestone, as many induced symptoms closely resembled those of schizophrenia and the drug showed selective affinity for the brain. The discovery of LSD-25 by Stoll and Hoffmann was even more significant because it worked similarly in infinitesimal amounts. Stoll (1947) proposed the pharmacological designation Phantastium for LSD-25 and classified the resulting model psychosis as acute.