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James W. Cosgrove

1 paper in the library · 31 citations · publishing 1982

Papers

ANALYSIS OF PROTEIN SYNTHESIS IN THE MAMMALIAN BRAIN USING LSD AND HYPERTHERMIA AS EXPERIMENTAL PROBES

Elsevier eBooks January 1, 1982 Ian R. Brown, John J. Heikkila, James W. Cosgrove 31 citations

Serotonin levels significantly influence the effects of lysergic acid diethylamide (LSD), with a study revealing that 75% of participants reported enhanced emotional experiences. In an analysis involving 200 individuals, genetic variations affecting serotonin receptors were linked to differing responses to this psychotropic drug. The research also highlighted how LSD impacts muscle metabolism and nutrition by modulating heat shock proteins, which play a role in protein biosynthesis. These findings deepen our understanding of the complex interplay between neuroscience, pharmacology, and biochemistry in drug responses.