Chronic intermittent exposure to ayahuasca during aging does not affect memory in mice
Brazilian Journal of Medical and Biological Research January 1, 2017 Nelson Francisco Correa-Netto, L.s. Coelho, G Galfano et al. 10 citations
Chronic exposure to ayahuasca over 12 months did not affect spatial reference memory, habituation, or anxiety in aging male mice. Twenty-eight 6-month-old male C57BL/6 mice received ayahuasca or water twice weekly for a year and were tested in the Morris water maze, open field, and elevated plus maze. Aging alone impaired memory retrieval (but not acquisition) and reduced locomotor activity, while anxiety remained unchanged. Ayahuasca treatment did not alter any of these age-related changes, suggesting that long-term ayahuasca use does not worsen or improve memory in mice.