Major depression: the relative contribution of gender, MDMA, and cannabis use
Depression and Anxiety March 7, 2007 Heather Durdle, Leslie H. Lundahl, Chris‐ellyn Johanson et al. 34 citations
Among 226 MDMA users, 11.5% met lifetime criteria for Major Depressive Disorder. No association was found between the number of MDMA uses and major depression. However, those with lifetime major depression had higher rates of lifetime cannabis use disorder (adjusted odds ratio 2.40). Logistic regression indicated that lifetime cannabis use disorder, but not MDMA use, was significantly associated with lifetime Major Depressive Disorder. For females, a lifetime cannabis use disorder was strongly associated with major depression (adjusted odds ratio 4.99), while for males, neither drug use variable was associated with major depression.